Insulin resistance score may predict stent failure
NCT ID NCT07614763
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at 1000 people who had a coronary stent placed to see if a score based on insulin resistance could predict whether the stent would narrow again (restenosis). Researchers measured insulin resistance using routine blood tests and checked for restenosis with follow-up angiography. The goal is to find a simple way to identify high-risk patients early.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors identify patients at higher risk of stent re-narrowing, leading to better follow-up care.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks for a link, so it cannot prove cause and effect or directly improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
1,000 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
We retrospectively collected the clinical data of patients with recurrent chest pain after PCI and requiring repeated angiography from January 2022 to November 2025, which were obtained from electronic medical records.
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥45 years * Patients with a history of percutaneous coronary intervention (PCI) with stent implantation * Patients who underwent repeat coronary angiography during follow-up * Complete clinical data available, including echocardiography, 24-hour ambulatory electrocardiogram, NT-proBNP, liver and kidney function tests, and blood biochemical tests Exclusion Criteria: * Previous coronary artery bypass grafting * Lesions treated only with balloon angioplasty without stent implantation * Clinical manifestations of heart failure, structural cardiomyopathy, congenital heart disease, or significant valvular heart disease * Severe hepatic or renal dysfunction, such as estimated glomerular filtration rate \<30 mL/min/1.73 m² * Incomplete clinical or angiographic data
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Qilu Hospital of Shandong University
Jinan, Shandong, 250012, China
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