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Diabetes drug may boost weight loss by targeting Brain's reward center

NCT ID NCT01239550

First seen Jan 24, 2026 · Last updated Apr 30, 2026 · Updated 13 times

Summary

This study looks at whether adding a low dose of the diabetes medication insulin detemir to a low-calorie diet helps obese adults with type 2 diabetes lose more weight and improve brain function related to food pleasure. About 240 participants will be split into two groups: one on diet only, the other on diet plus insulin detemir. The study lasts 26 weeks and includes hospital stays, blood tests, and brain scans.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Vanderbilt University

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.