Heart failure drug combo: is starting both at once safe?
NCT ID NCT05989503
First seen Nov 19, 2025 · Last updated May 01, 2026 · Updated 22 times
Summary
This study looked at 62 adults with heart failure and reduced pumping ability. Researchers compared starting two medications (sacubitril/valsartan and an SGLT2 inhibitor) at the same time versus starting one drug first and adding the other later. The goal was to see which approach is safer over 6 months by tracking side effects like low blood pressure, kidney problems, and hospital visits.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centro Hospitalar Universitário São João
Porto, 4200-319, Portugal
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Centro Hospitalar Universitário de Santo António
Porto, Porto District, 4099-001, Portugal
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Centro Hospitalar Vila Nova de Gaia/Espinho
Porto, 4434-502, Portugal
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Faculty of Medicine (FMUP)
Porto, 4200-319, Portugal
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Unidade Local de Saúde de Matosinhos - Hospital Pedro Hispano
Porto, Portugal
Conditions
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