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Simple blood test may predict fertility treatment success

NCT ID NCT07415928

Knowledge-focused Sponsor: Elazıg Fethi Sekin Sehir Hastanesi Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a blood test measuring certain hormones (Inhibin B and FSH) can predict the type of testicular damage in men with a condition called non-obstructive azoospermia, where no sperm are found in the semen. Researchers analyzed data from 73 men who had a surgical sperm retrieval procedure. They found that the ratio of these hormones could help distinguish between different patterns of testicular tissue damage, potentially guiding treatment decisions and avoiding unnecessary surgery in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test that helps doctors predict sperm retrieval success in men with azoospermia, avoiding unnecessary surgery.
What could go wrong
This is a small, single-center observational study. The findings need to be confirmed in larger, more diverse groups before they can be used in routine practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

73 people

The number who actually took part.

Started

Jan 2026

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult male patients diagnosed with non-obstructive azoospermia who underwent micro-TESE at a tertiary referral center and had available histopathological and hormonal evaluation data.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male patients who underwent micro-TESE for non-obstructive azoospermia * Available histopathological evaluation of testicular tissue * Available preoperative serum hormone measurements (FSH, LH, testosterone, Inhibin B) Exclusion Criteria:• Obstructive azoospermia * Incomplete clinical, hormonal, or histopathological data * Previous testicular malignancy * History of chemotherapy or radiotherapy affecting spermatogenesis

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Conditions

The condition(s) this trial relates to.

azoospermia spermatogenic failure 3 spermatogenic failure, Y-linked, 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Azoospermia, nonobstructive Non-obstructive azoospermia

Contacts and locations

Locations

  • Elazığ Fethi Sekin City Hospital

    Elâzığ, 23100, Turkey (Türkiye)

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