Smaller cut, same hope: study seeks to predict sperm retrieval success
NCT ID NCT07286279
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 248 men with very low or no sperm in their semen to see if a less-invasive, mini-incision surgery could successfully retrieve sperm. Researchers checked whether factors like hormone levels or medical history could predict who would benefit from this smaller procedure. The goal is to help men avoid more extensive surgery when a simpler approach might work.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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248 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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Jan 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Men who underwent micro-TESE procedure from March 2015 to June 2025
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with cryptozoospermia or non obstructive azoospermia that underwent a micro-TESE Exclusion Criteria: * Patients with a potentially reversible cause of cryptozoospermia (i.e., presence of a varicocele, febrile illness, or recent toxin exposure) * Patients with suspected partial genital tract obstruction (i.e post-vaso-vasostomy, post-vasoepididymostomy, and low volume cryptozoospermia with ejaculatory duct obstruction) * Patients who have previously undergone a micro-TESE, TESA or TESE procedure
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinique ovo
Montreal, Quebec, H4P 2S4, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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