Scientists probe immune secrets of four skin diseases
NCT ID NCT03976622
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to understand inflammation in four chronic skin conditions: vitiligo, psoriasis, eczema (atopic dermatitis), and alopecia areata. Researchers will collect blood and small skin samples from 450 adults to analyze immune cells called T-cells. The goal is to describe how these cells differ in each disease, which may help guide future treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could reveal new targets for treating chronic inflammatory skin diseases.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly benefit participants and may not lead to new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 450 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2020
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
450 patients (300 patients with vitiligo, 50 psoriasis patients, 50 patients with atopic dermatitis, 50 patients with alopecia areata)
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 to 75 years; * Patients with non-segmental vitiligo; * Patients with plaque psoriasis; * Patients with atopic dermatitis; * Patients with alopecia areata sclerosis; * written consent, free, informed and signed by the patient and the investigator (before any examination required by the study); * Subject affiliated or beneficiary of a social security system. Exclusion Criteria: * Patients with segmental vitiligo * Patients under local treatment (topical corticosteroid-Calcineurin inhibitor) for less than two weeks. * Patients on therapy, systemic treatments: acitretin, methotrexate, cyclosporine, Apremilast, infliximab, adalimumab, etanercept, ustekinumab, secukinumab, ixekizumab, dupilumab) for less than 4 weeks. * Pregnant or breastfeeding women * Patient (e) under guardianship * Patient (e) Non-affiliated (e) a social protection
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Service de Dermatologie - Hôpital Saint-André
Bordeaux, Bordeaux, 33075, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Skin scans may predict who responds to dupilumab for eczema
- Can a daily liquid medicine calm severe eczema in toddlers and preschoolers?
- Can an oral drug tame hair loss? 7,500-Patient study tracks ritlecitinib in real life
- Scientists probe whether lebrikizumab rewires diseased skin at the molecular level
- Can a skin cream bring back color to faces with vitiligo?
- Can a Once-Daily moisturizer help psoriasis skin? patients put it to the test