Swiss study aims to curb antibiotic overuse with new guidelines

NCT ID NCT07396428

Knowledge-focused Sponsor: Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether implementing new Swiss national guidelines for acute respiratory infections can reduce unnecessary antibiotic prescribing in primary care. Researchers will work with 200 family doctors in quality circles and walk-in clinics, providing training and materials to support targeted use of CRP testing and shared decision-making. The goal is to slow antibiotic resistance by cutting down on antibiotics for viral infections, where they don't work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: Training session on acute respiratory infection guideline within a multifaceted implementation strategy
What this could lead to: If successful, this could provide a proven way to reduce unnecessary antibiotic use in primary care, helping to slow antibiotic resistance.
What could go wrong: This is an implementation study, not a drug trial, so it won't directly treat disease. Results depend on doctors voluntarily following guidelines, and success may vary across clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria for quality circles (QCs) * Willing to participate in a study mainly conducted in French * Agreeing to participate in evaluation surveys Exclusion criteria for QCs\* \- Not having any physician included in the study Inclusion criteria for walk-in clinics * The clinic offers general practice/primary care medicine consultations, including emergencies * The clinic includes at least five physicians * The clinic has an "Admission to practice charged to Swiss compulsory health insurance" * The clinic plans to still be active in April 2026 * Located in one of the following cantons: Vaud, Geneva, Valais, Fribourg, Jura, Neuchatel, Bern, Ticino. * Serving mainly adult patients * Willing to participate in the study Physicians in QCs fulfilling all of the following inclusion criteria are eligible for the study: * Registered primary care physicians * Specialist title in general internal medicine or practicing physician. * Practicing in one of the following cantons: Vaud, Geneva, Valais, Fribourg, Jura, Neuchatel, Bern, Ticino. * Participating in a QC or working in an outpatient clinic participating in the study\*. * Willing to participate in a study mainly conducted in French. * Agreeing to participate in evaluation surveys and agreeing to be invited to interviews Eligibility criteria for physicians in clinics : \- Having a clinical activity as primary care physician or supervising clinical activity of physicians in post-graduate training within a clinic included in the study The only exclusion criterion for physicians is planning to retire before April 2026. \*Note: not all physicians from a QC or a clinic are expected or required to participate individually in the study, but at least one should participate.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory infection Influenza -like illness

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Swiss study aims to curb antibiotic overuse with new guidelines

What the study statuses mean