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Immunotherapy duo shows promise in shrinking colorectal tumors before surgery

NCT ID NCT05571293

First seen May 31, 2026 · Last updated Jun 13, 2026 · Updated 1 time

Summary

This study tests whether giving two immunotherapy drugs (botensilimab and balstilimab) before surgery can help shrink colorectal cancer tumors in 26 adults. The drugs aim to boost the immune system to attack the cancer. Researchers are checking how well the tumors respond and what side effects occur. This is not a cure, as ongoing monitoring and potential further treatment are needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Weill Cornell Medicine/New York-Presbyterian Brooklyn Methodist Hospital

    Brooklyn, New York, 11215, United States

  • Weill Cornell Medicine/NewYork Presbyterian - Queens

    Flushing, New York, 11355, United States

  • Weill Cornell Medicine/NewYork-Presbyterian Hospital

    New York, New York, 10021, United States

Conditions

The condition(s) this trial relates to.

colorectal cancer Colorectal Neoplasms Diabetes Mellitus, Insulin-Dependent, 12

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.