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IVF breakthrough? study tests if immediate embryo transfer boosts birth rates

NCT ID NCT04371783

Knowledge-focused Sponsor: ShangHai Ji Ai Genetics & IVF Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether transferring a frozen embryo in the first menstrual cycle after egg retrieval leads to more live births than waiting until the second cycle. Over 800 women undergoing their first frozen embryo transfer are randomly assigned to immediate or delayed transfer. The goal is to find the best timing for IVF success.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If immediate transfer works better, it could simplify IVF treatment and shorten the time to pregnancy for many women.
What could go wrong
This is a single-center study in China, so results may not apply to all IVF patients. The difference in live birth rates may be small or not significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 828 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2020

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Women aged 20-40 years at the time of IVF/ICSI 2. Women undergoing their first FET of the first IVF cycle following a freeze-all strategy 3. Undergoing IVF with GnRH antagonist 4. At least one frozen blastocyst Exclusion Criteria: 1. Severe ovarian hyperstimulation syndrome during the first IVF/ICSI cycle 2. Preimplantation genetic testing 3. Use of donor oocytes 4. Presence of untreated hydrosalpinx or endometrial polyp on scanning during ovarian stimulation

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Conditions

The condition(s) this trial relates to.

ventricular fibrillation, paroxysmal familial, type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Frozen embryo transfer IVF

Contacts and locations

Locations

  • Shanghai JiAi Genetics & IVF Institute

    Shanghai, Shanghai Municipality, 200011, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.