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Text therapy could boost opioid recovery

NCT ID NCT04808479

Disease control Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study tests a text-message-based cognitive behavioral therapy (CBT) program called imFREE to help adults with opioid use disorder stick with their buprenorphine treatment and reduce opioid use. Participants receive daily text messages with CBT skills and relapse prevention tips. The trial compares imFREE to a standard health education program over 32 weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
imFREE mCBT (text-message cognitive behavioral therapy)
What this could lead to
If effective, imFREE could offer a low-cost, scalable way to improve medication adherence and reduce opioid use in people with opioid use disorder.
What could go wrong
This is a relatively small, early-stage behavioral trial. The intervention may not work better than standard education, and results may not apply to everyone with opioid use disorder.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

210 people

The number who actually took part.

Started

Dec 2019

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \> 18 * DSM-5 diagnosis of OUD * no more than 2 weeks from the date of BUP induction * able to read and comprehend English at the 6th grade level (determined by REALM) * able to provide informed consent * presently owns a mobile phone that can send and receive text messages EXCLUSION CRITERIA Participants must not have: 1. Life threatening or unstable medical illness requiring treatment or making participation difficult 2. Dependence on alcohol or other illicit substances for which medical detoxification is imminently needed 3. Presence of acute psychiatric symptoms warranting intensive treatment or hospitalization (e.g., acute suicidality or mania).

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid-use disorder

Contacts and locations

Locations

  • Tarzana Treatment Center

    Tarzana, California, 91356, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.