New scan may replace costly imaging for prostate cancer patients
NCT ID NCT06828263
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a special type of scan (LuPSMA-SPECT/CT) can tell doctors early if a targeted radiation therapy is working in men with advanced prostate cancer that no longer responds to hormone therapy. About 130 participants will be followed to see if changes on the scan match how long they live. If successful, this could replace more expensive PET scans and help doctors switch treatments sooner.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 130 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2023
- Expected to finish
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Dec 2043
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients from the investigator's department only
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult aged 18 or older with proven adenocarcinoma of the prostate * Diagnosis of progressive metastatic castration-resistant prostate cancer. * Progression or intolerance on a novel anti-androgen therapy (i.e. abiraterone, enzalutamide, apalutamide or darolutamide) * Prior therapy with at least one taxane-based chemotherapy during the course of prostate cancer or the patient is symptomatic and assessed as unfit for chemotherapy. * ECOG Performance status 0 to 2 Exclusion Criteria: * Patient opposed to the use of his data for clinical research.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU Grenoble Alpes
RECRUITINGGrenoble, 38053, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Glow-in-the-dark dye may help surgeons spot hidden prostate cancer cells
- Radiation zaps prostate cancer spots in men not helped enough by hormone drugs
- New Imaging-Guided combo therapy aims to slow prostate cancer spread
- Could a special PET scan spot returning prostate cancer sooner?
- Lab-Grown Mini-Tumors could predict best prostate cancer therapy
- Could a common ED drug shield prostate cancer patients from chemo nerve pain?