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New brain scan tracer could unlock secrets of depression and Alzheimer's

NCT ID NCT06874205

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This study tests a new radioactive tracer called 11C-JMJ-129 that attaches to a protein called PDE4D in the body, which is linked to thinking and mood. Healthy volunteers aged 18 and older will have PET and MRI scans to see how well the tracer works. The goal is to improve future research into conditions like Alzheimer's disease and major depression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.