Rewriting traumatic panic memories: a new therapy on trial
NCT ID NCT07769996
First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time
Summary
This trial tests whether a 6-session therapy called Imagery Rescripting (ImRs) can reduce panic disorder symptoms by changing how people recall and process traumatic panic attack memories. Adults diagnosed with panic disorder are randomly assigned to receive the therapy or be in a control group. Researchers measure changes in symptom severity and physical arousal (heart rate and skin conductance) during memory recall, right after treatment and one month later.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Imagery Rescripting (ImRs), a psychological therapy that helps people change the emotional impact of distressing memories
- What this could lead to
- If effective, this therapy could offer a new, drug-free way to reduce panic symptoms by targeting the traumatic memories that fuel them.
- What could go wrong
- This is a small, early-stage trial, so results may not apply broadly. The therapy may not outperform the control, and benefits may not last beyond one month.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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32 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Being aged between 18 and 65 years. Voluntarily agreeing to participate in the study and providing informed consent. Being fluent in written and spoken Turkish. Having a current diagnosis of Panic Disorder according to DSM-5 criteria, confirmed by a psychiatrist. Answering "No" to the traumatic event screening question regarding the index panic memory (i.e., the panic memory does not involve exposure to actual or threatened death, serious injury, or physical threat). Exclusion Criteria: Being under 18 or over 65 years of age. Inability or unwillingness to provide informed consent. Insufficient Turkish literacy. Absence of a current psychiatric diagnosis of Panic Disorder according to DSM-5 criteria. Having a lifetime diagnosis of Post-Traumatic Stress Disorder (PTSD) according to DSM-5 criteria. Answering "Yes" to the traumatic event screening question (i.e., presence of an explicit Criterion A traumatic event/physical threat in the index memory).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bağcılar Eğitim ve Araştırma Hastanesi
Istanbul, Bağcılar, Turkey (Türkiye)
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