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Can exercise protect aging muscles? new study seeks answers

NCT ID NCT03118050

Knowledge-focused Sponsor: The University of Texas Medical Branch, Galveston Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study looked at how muscle size and strength change in older adults with type 2 diabetes during bed rest and exercise. Researchers studied 95 participants to find targets for future treatments to prevent muscle loss and disability. The goal is to improve health and independence in our aging population.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new treatments to slow muscle loss and disability in older adults, especially those with diabetes.
What could go wrong
This is an observational study, not a treatment trial. The findings may not directly lead to therapies, and results may not apply to all older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

95 people

The number who actually took part.

Started

May 2017

Finished

Aug 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Body mass index: \<40 kg/sq meter * Score ≥26 on the 30-item Mini Mental State Examination * Stable body weight for at least 3 months * Non-diabetic or with Type 2 Diabetes Mellitus Exclusion Criteria: * Pre-diabetes per American Diabetes Association criteria * Insulin therapy, significant diabetic complications, or A1c\>8% * Impairment in Activities of Daily Living * \>2 falls/year * weight loss \>5% in the past 6 months * Exercise training (≥2 sessions/week) or ≥10,000 steps/day * Significant cardiovascular, liver, renal, blood, or respiratory disease * Active cancer or infection * Recent (within 3 months) treatment with anabolic steroids, systemic corticosteroids or estrogen. * Alcohol or drug abuse

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Motor Activity Sarcopenia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Diabetes mellitus Sarcopenia

Contacts and locations

Locations

  • Sealy Center on Aging, University of Texas Medical Branch

    Galveston, Texas, 77550, United States

More trials for these conditions

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