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Freezing heart rhythms: new device aims to tame stubborn AFib

NCT ID NCT04061603

First seen Apr 18, 2026 · Last updated May 23, 2026 · Updated 7 times

Summary

This study tested a new freezing device (iCLAS™) to treat persistent atrial fibrillation, a type of irregular heartbeat lasting over a week. 215 adults aged 18-80 received the procedure to see if it safely restores normal rhythm. The goal was to reduce serious complications and prevent arrhythmia recurrence.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Banner Health

    Phoenix, Arizona, 85006, United States

  • Baylor St. Luke's Medical Center

    Houston, Texas, 77030, United States

  • Emory St. Joseph's Hospital

    Atlanta, Georgia, 30342, United States

  • Erasmus University Medical Center

    Rotterdam, 3015 GD, Netherlands

  • Grandview Medical Center

    Birmingham, Alabama, 35243, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • New Mexico Heart Institute

    Albuquerque, New Mexico, 87102, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Ohio Health Research Institute

    Columbus, Ohio, 43214, United States

  • Onze Lieve Vrouwziekenhuis

    Aalst, Belgium

  • Prairie Heart Research Institute

    Springfield, Illinois, 62701, United States

  • South Denver Cardiology Associates

    Denver, Colorado, 80120, United States

  • Southlake Regional Medical Centre

    Newmarket, Ontario, L3Y 2P9, Canada

  • St. Antonius Ziekenhuis Nieuwegein

    Nieuwegein, Netherlands

  • St. Bernards Medical Center

    Jonesboro, Arkansas, 72401, United States

  • Staten Island University Hospital - Northwell Health

    Staten Island, New York, 10305, United States

  • The Valley Hospital

    Ridgewood, New Jersey, 07450, United States

  • University of California San Diego

    San Diego, California, 92093, United States

  • ZNA Middelheim

    Antwerp, Belgium

Conditions

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