New freezing technique shows promise for stubborn heart flutter

NCT ID NCT04061603

First seen Apr 18, 2026 · Last updated Apr 23, 2026 · Updated 1 time

Summary

This study tested a new device that uses extreme cold to destroy small areas of heart tissue causing persistent atrial fibrillation (a type of irregular heartbeat). 215 adults with this condition were treated. The goal was to see if the procedure is safe and effectively restores normal heart rhythm without needing long-term medication. This is a disease control approach, not a cure, as the underlying condition may still require management.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Banner Health

    Phoenix, Arizona, 85006, United States

  • Baylor St. Luke's Medical Center

    Houston, Texas, 77030, United States

  • Emory St. Joseph's Hospital

    Atlanta, Georgia, 30342, United States

  • Erasmus University Medical Center

    Rotterdam, 3015 GD, Netherlands

  • Grandview Medical Center

    Birmingham, Alabama, 35243, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21205, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • New Mexico Heart Institute

    Albuquerque, New Mexico, 87102, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Ohio Health Research Institute

    Columbus, Ohio, 43214, United States

  • Onze Lieve Vrouwziekenhuis

    Aalst, Belgium

  • Prairie Heart Research Institute

    Springfield, Illinois, 62701, United States

  • South Denver Cardiology Associates

    Denver, Colorado, 80120, United States

  • Southlake Regional Medical Centre

    Newmarket, Ontario, L3Y 2P9, Canada

  • St. Antonius Ziekenhuis Nieuwegein

    Nieuwegein, Netherlands

  • St. Bernards Medical Center

    Jonesboro, Arkansas, 72401, United States

  • Staten Island University Hospital - Northwell Health

    Staten Island, New York, 10305, United States

  • The Valley Hospital

    Ridgewood, New Jersey, 07450, United States

  • University of California San Diego

    San Diego, California, 92093, United States

  • ZNA Middelheim

    Antwerp, Belgium

Conditions

Explore the condition pages connected to this study.