Your genes may determine how well ibuprofen works for tooth pain
NCT ID NCT05983042
First seen Jun 05, 2026 · Last updated Jun 23, 2026 · Updated 3 times
Summary
This study in 200 healthy Pakistani adults looked at whether a common gene variation (CYP2C9*3) changes how well ibuprofen works for pain after a molar tooth extraction. Participants took ibuprofen or a placebo, and researchers measured pain levels and side effects. The goal was to see if genetics could help predict who gets the best pain relief with the fewest side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Ammarah Amjad
Rawalpindi, Punjab Province, 46000, Pakistan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ibuprofen 400 mg
What this could lead to
If successful, this could help doctors personalize painkiller choices based on a person's genetics, improving pain relief and reducing side effects.
What could go wrong
This is a small, completed observational study in a specific population, so results may not apply to other groups. It does not test a new treatment.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.