Your genes may determine how well ibuprofen works for tooth pain
NCT ID NCT05983042
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study in 200 healthy Pakistani adults looked at whether a common gene variation (CYP2C9*3) changes how well ibuprofen works for pain after a molar tooth extraction. Participants took ibuprofen or a placebo, and researchers measured pain levels and side effects. The goal was to see if genetics could help predict who gets the best pain relief with the fewest side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ibuprofen 400 mg
- What this could lead to
- If successful, this could help doctors personalize painkiller choices based on a person's genetics, improving pain relief and reducing side effects.
- What could go wrong
- This is a small, completed observational study in a specific population, so results may not apply to other groups. It does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ammarah Amjad
Rawalpindi, Punjab Province, 46000, Pakistan
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