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New hope for rare brain cancer: targeted drug shows promise in relapsed patients

NCT ID NCT05782374

First seen Jan 10, 2026 · Last updated May 24, 2026 · Updated 27 times

Summary

This study reviews medical records of 36 adults with a rare and aggressive brain lymphoma (PCNSL) that has come back or not responded to prior treatment. Researchers want to see how well the targeted drug ibrutinib works, either alone or combined with standard chemotherapy (R-CHOP). The goal is to measure tumor shrinkage and how long patients live without the disease getting worse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ospedale San Raffaele

    Milan, Italy, 20132, Italy

Conditions

Explore the condition pages connected to this study.