New hope for rare brain cancer: ibrutinib shows promise in relapsed PCNSL

NCT ID NCT05782374

First seen Jan 10, 2026 · Last updated May 14, 2026 · Updated 25 times

Summary

This study reviews medical records of 36 adults with relapsed or refractory PCNSL, a rare and aggressive brain lymphoma. Researchers want to see how well ibrutinib works alone or combined with R-CHOP chemotherapy. The goal is to measure tumor shrinkage and survival, while checking safety.

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Contacts and locations

Locations

  • Ospedale San Raffaele

    Milan, Italy, 20132, Italy

Conditions

Explore the condition pages connected to this study.