Do heart meds cause low blood sugar in kids? new study investigates
NCT ID NCT07233421
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study looks at how often low blood sugar (hypoglycemia) occurs in children under 7 with Long QT syndrome who take the beta-blocker propranolol. Researchers will use a continuous glucose monitor for 10 days during healthy times and during an infection. They will compare results with healthy siblings to see if the medication raises the risk of low blood sugar, which could affect well-being and development.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Up to 7 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Study group: children under 7 years of age with genetically confirmed LQTS (types 1 or 2) and on beta-blocker medication * Control group: healthy children (siblings of LQTS patients) Exclusion Criteria: -Children with diabetes, inherited diseases of inborn error of metabolism, tube feeding, gastrointestinal operations with risk for dumping, medications leading to hypoglycemia, dialysis, or any severe acute illness
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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New Children's Hospital, Helsinki University Hospital
Helsinki, Finland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Mapping the hormone behind Post-Surgery blood sugar crashes
- Can a treadmill test predict a Child's heart rate at play?
- Can hormones during pregnancy reshape the Heart's electrical beat?
- Can hidden heart rhythms explain dialysis risks?
- Could a glucose monitor and education shield seniors from Insulin's dangerous side?