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Oxygen chamber muscle boost? small study tests the idea
NCT ID NCT07558928
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a single session of hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can increase muscle strength in healthy, physically active adults aged 18 to 45. Participants will do a mid-thigh pull test after either the real oxygen treatment or a sham (fake) version, and the results will be compared. The trial is small (48 people) and aims to gather knowledge, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)
- What this could lead to
- If it works, this could suggest that hyperbaric oxygen might temporarily enhance muscle performance in healthy people.
- What could go wrong
- This is a very small, early study in healthy volunteers, not patients. The effect, if any, may be tiny or not meaningful for real-world use. There is no disease being treated.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy 2. Ages 18-45 3. Participants are physically active and have a recent resistance-training experience of at least six months, ≥ 3 times a week 4. Participant willing and able to read, understand and sign an informed consent Exclusion Criteria: 1. Inability to attend scheduled clinic visits or comply with the study protocol 2. Active malignancy 3. Active smokers 4. Previous treatment of hyperbaric chamber for any reason prior to study enrollment. 5. Chest pathology incompatible with pressure changes 6. Major orthopedic injury at the past 3 months 7. Inner ear disease 8. Lung pathology 9. Claustrophobia 10. Previous neurologic conditions (e.g., epilepsy, brain tumors or s/p neurosurgery etc.) 11. Comorbidities and medications that rule out the subject
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center
RECRUITINGZrifin, Israel
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