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Scientists hunt for brown Fat's secret signals in the blood

NCT ID NCT05050240

Knowledge-focused Sponsor: Rockefeller University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to discover molecules released by brown fat into the blood that could serve as easy-to-measure markers of metabolic health. Researchers will analyze blood samples from 20 healthy young adults before and after mild cold exposure to activate brown fat. The goal is to find non-invasive biomarkers that could eventually help predict or understand conditions like obesity and diabetes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 28 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 28 * BMI \>19 and \< 25 Exclusion Criteria: * Diabetes type I or II (self-report) * Diagnosis of thyroid disease (including goiter, hyperthyroidism, hypothyroidism, thyroiditis) (self-report) * Diagnosis with cancer including skin cancer (self-report) * Diagnosis or evidence of Raynaud's Syndrome or systemic sclerosis (self report) * Previously or currently diagnosed with SARS-Cov-2 infection/COVID-19 (secondary to unknown immune responses) * Any vaccine administration within two weeks preceding the study procedure * Currently pregnant * Currently taking any prescribed medication other than oral contraceptives * Treatments for weight loss or any other supplements that may alter weight or metabolism are not acceptable (vitamins are acceptable) * Has consumed nicotine (smoking, inhaling, ingesting) within the last within the last 6 months * Has used illicit drugs within the last 6 months * Any medical, psychological, or social condition that, in opinion of principle investigators, would jeopardize the health or well-being of the participant during the study procedure or integrity of the data

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy lifestyle

Contacts and locations

Locations

  • The Rockefeller University Hospital

    New York, New York, 10065, United States

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