Could a household chemical supercharge breast cancer radiation?
NCT ID NCT03946202
First seen Apr 05, 2026 · Last updated Jun 22, 2026 · Updated 11 times
Summary
This study tests whether injecting a very dilute hydrogen peroxide solution directly into breast tumors can make standard radiotherapy more effective. Researchers are enrolling 184 adults with locally advanced or recurrent breast cancer. Participants will receive injections twice a week during their radiation course, and doctors will monitor tumor shrinkage and survival over two years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beatson West of Scotland Cancer Centre
RECRUITINGGlasgow, Scotland, G12 0YN, United Kingdom
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Cambridge University Hospitals NHS Foundation Trust
RECRUITINGCambridge, CB2 0QQ, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Christian Medical Centre
RECRUITINGVellore, Tamil Nadu, 632004, India
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Regional Cancer Centre (RCC)
RECRUITINGTrivandrum, Kerala, 695011, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Cornwall Hospitals NHS Trust
RECRUITINGTruro, Cornwall, TR1 3LJ, United Kingdom
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Tata Medical Centre
RECRUITINGKolkata, West Bengal, 700160, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tata Memorial Centre
RECRUITINGMumbai, India
Contact Email: •••••@•••••
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The Christie NHS Foundation Trust
RECRUITINGManchester, M20 4BX, United Kingdom
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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The Royal Marsden NHS Foundation Trust
RECRUITINGSutton, SM2 5PT, United Kingdom
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact
Contact
Contact
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University Hospitals of North Midlands NHS Trust
RECRUITINGStoke-on-Trent, ST4 6QG, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hydrogen peroxide
What this could lead to
If it works, this could offer a cheap, widely available way to make radiotherapy more effective for hard-to-treat breast cancers.
What could go wrong
This is a phase 2 trial with only 184 participants, and the promising results so far come from a small Japanese study. The treatment may not work as well in a larger, more diverse group.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.