Joint gel injection after surgery shows promise in tiny trial
NCT ID NCT07468045
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether injecting hyaluronic acid into the knee or shoulder right after arthroscopic surgery helps with recovery and pain control. Nine adults aged 18 to 60 who had scheduled arthroscopy received the injection during their procedure. Researchers measured safety, range of motion, and pain scores over 24 weeks to see if the treatment improved outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hyaluronic acid
- What this could lead to
- If it works, this could point toward a way to help people recover faster and with less pain after joint surgery.
- What could go wrong
- This was a very small study with only 9 people, so results may not apply to everyone. It also did not compare against a placebo, so benefits are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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9 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Jul 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Male and female adults aged 18 to 60 years at the date of the written informed consent form. 2. Patient with surgery scheduled for arthroscopic procedure on knee or shoulder. 3. Those who could understand the provided information and were able to fill out the questionnaire. 4. Those who voluntarily decided to participate in the study and wrote the informed consent form. Exclusion Criteria: 1. In the following cases that may affect test results 1. Patients with history and suspected of rheumatoid arthritis (RA). 2. Patients with osteoarthritis in the joint related to specific joint movement. 3. Those with a history of surgery in the related area of the join that affect join movement. 4. Patients with infection at the surgical site. 2. Patients with chronic diseases that may affect surgery, such as uncontrolled diabetes or uncontrolled high blood pressure. 3. Patients with complex regional pain syndrome. 4. If adverse reactions are expected during surgery in the following cases: 1. People taking blood coagulants or patients with diseases that require blood coagulants. 2. When there are restrictions on the use of anticoagulants or antithrombotic agents. 3. Those with confirmed severe liver dysfunction or decreased renal function. 4. Patients with other serious systemic diseases such as severe anemia. 5. Known HIV positive person receiving medication. 5. Patients are allergic to substances used in medical devices for the study (Hyaluronic Acid). 6. Pregnant, lactating, or women of childbearing potential who are unwilling to use contraception during the study. 7. Use of drugs or medical devices due to participation in other study 8. Other people deemed inappropriate to participate in the test by the investigator (including high probability of noncompliance).
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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MRCCC Siloam Hospitals Semanggi
Jakarta, 12930, Indonesia
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Siloam Hospitals Mampang
Jakarta, 12760, Indonesia
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