New shot could ease knee replacement pain without opioids
NCT ID NCT03015532
First seen Mar 04, 2026 · Last updated May 20, 2026 · Updated 9 times
Summary
This study tested a new pain medicine called HTX-011 in 285 people having knee replacement surgery. The medicine was given as a shot into the knee during surgery to see if it could control pain better than a placebo or standard treatment. The goal was to reduce pain and the need for opioid painkillers after the operation.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Study site
Mobile, Alabama, 36608, United States
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Study site
Sheffield, Alabama, 35660, United States
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Study site
Phoenix, Arizona, 85015, United States
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Study site
Phoenix, Arizona, 85023, United States
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Study site
La Jolla, California, 92037, United States
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Study site
Riverside, California, 92503, United States
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San Diego, California, 92103, United States
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Study site
Miami, Florida, 33136, United States
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Study site
Miami, Florida, 33143, United States
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Study site
Miami, Florida, 33155, United States
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Study site
Tamarac, Florida, 33321, United States
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Study site
Las Vegas, Nevada, 89109, United States
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Study site
Columbus, Ohio, 43203, United States
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Study site
Columbus, Ohio, 43210, United States
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Study site
Dayton, Ohio, 45417, United States
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Study site
Bellaire, Texas, 77401, United States
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Study site
Houston, Texas, 77004, United States
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Study site
Houston, Texas, 77027, United States
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Study site
Houston, Texas, 77043, United States
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Study site
Plano, Texas, 75093, United States
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Study site
San Antonio, Texas, 78209, United States
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Study site
San Antonio, Texas, 78229, United States
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Study site
San Antonio, Texas, 78240, United States
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Study site
Webster, Texas, 77598, United States
Conditions
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