Could a pill stop Alzheimer's before it starts? new trial targets High-Risk gene carriers
NCT ID NCT07399171
First seen Feb 12, 2026 · Last updated May 22, 2026 · Updated 12 times
Summary
This study tests an experimental drug, HT-4253, to see if it can lower the risk of developing Alzheimer's disease in people who carry the APOE4 gene variant, which increases risk. The trial will include 112 participants aged 50-75 who have early signs of amyloid buildup in the brain but no memory loss yet. Half will receive the drug and half a placebo for 48 weeks, and researchers will measure changes in blood markers related to Alzheimer's.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic Abu Dhabi
Abu Dhabi, United Arab Emirates
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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