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New drug combo shows promise for shrinking pancreatic tumors before surgery

NCT ID NCT06587061

First seen May 30, 2026 · Last updated Jun 16, 2026 · Updated 2 times

Summary

This study is testing whether adding the experimental drug HRS-4642 to standard chemotherapy can help shrink pancreatic tumors before surgery and prevent them from coming back after surgery. About 30 adults with resectable or borderline resectable pancreatic cancer will receive the combination treatment. The main goals are to see how safe the treatment is and how many patients' tumors shrink enough for successful surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma malignant pancreatic neoplasm pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.