Simple clinic training may help more kids get HPV vaccine
NCT ID NCT05742386
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests whether training primary care clinics to better use HPV vaccine standing orders can increase vaccination rates in children ages 9-12. Some clinics receive communication training alone, while others also get help optimizing their standing orders. The study uses vaccination data from children and surveys from clinic staff, but does not enroll children directly.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Communication training and standing orders optimization
- What this could lead to
- If successful, this could provide a simple, scalable way for clinics to increase HPV vaccination rates, helping prevent HPV-related cancers.
- What could go wrong
- This is a small, early-stage trial with only 27 clinics, so results may not apply broadly. The intervention focuses on clinic workflow, not a new vaccine or drug, so impact may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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27 people
The number who actually took part.
- Started
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Feb 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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9 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
This trial will enroll clinics and intervene with clinical staff. We will use vaccination data from children and survey data from clinical staff to evaluate intervention effectiveness. We will not enroll children or interact with them directly. Inclusion Criteria Clinics are eligible if they: * provide HPV vaccine to children ages 9-12 * have standing orders for HPV vaccination approved but not routinely used or be willing to adopt them prior to the start of the trial * have rates of HPV vaccination (≥1 dose) below 72%, boys and girls combined Children's medical records will be eligible to be included in the dataset if children: * are between the ages of 9-12 years at baseline * are attributed to a participating clinic at 12- or 24-month follow-up Clinical staff's survey data will be eligible to be included in the dataset if clinical staff complete the follow-up survey. Exclusion Criteria Clinics are excluded if they: * do not provide HPV vaccine to children ages 9-12 * do not have standing orders for HPV vaccination or are not willing to adopt them prior to the start of the trial * have rates of HPV vaccination (≥1 dose) above 72%, boys and girls combined * have hosted an AAT workshop in the previous 3 years or are part of current HPV vaccine communication trainings * have quality improvement efforts to change HPV vaccine standing orders during the trial Children's medical records will not be eligible to be included in the dataset if children: * are not between the ages of 9-12 years at baseline * are not attributed to a participating clinic at 12- or 24-month follow-up * are receiving hospice/palliative care, are pregnant, or have a history of HPV vaccine contraindications Clinical staff's survey data will be not eligible to be included in the dataset if clinical staff do not complete the follow-up survey.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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Other studies related to the condition(s) this trial covers.
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