Tweets that tell a story: a new approach to boosting HPV vaccination
NCT ID NCT05204030
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial investigates whether narrative (story-based) messages on Twitter are more effective than factual messages at encouraging parents to vaccinate their children against HPV. Parents of children aged 9–14 who have not started the HPV vaccine series will be randomly assigned to see either storytelling or fact-based tweets. The study measures whether the messages increase empathy, engagement, and ultimately, vaccination rates.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- HPV Twitter Education Program - Narrative and Non-Narrative messages
- What this could lead to
- If storytelling on social media proves more effective, it could offer a low-cost way to boost HPV vaccination rates and reduce vaccine-preventable cancers.
- What could go wrong
- This is a small, early-stage trial with only 28 participants, so results may not apply broadly. Social media engagement does not always translate into actual vaccination.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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28 people
The number who actually took part.
- Started
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Dec 2021
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: The study population includes parents who have children ages 9-14. All participants will be 18 years of age or older, and we will specifically target parents ages 25 and older. Eligibility for enrollment in the study will be limited to the following criteria: 1. Adults 18 years of age and older; 2. Utilizes Twitter, a social media platform; 3. Has a child aged 9-14; 4. Child has not started the 2-dose HPV vaccination series; 5. Has no child who has completed any dose HPV vaccination series; 6. Has a well-care visit scheduled for their child before December, 2022. Exclusion Criteria: 1. Any adult who does not have a child 9-14 years of age; 2. Any adult who does not indicate some level of participation in Twitter; 3. Any adults who indicates a high level of anti-vaccine sentiment (assessed by vaccine hesitancy questions asked in the screener).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Arkansas
Fayetteville, Arkansas, 72701, United States
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Other studies related to the condition(s) this trial covers.
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