Scientists probe how stress and pain shape your choices
NCT ID NCT05666726
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 29 times
Summary
This study looks at how negative emotions like stress, pain, and frustration change the way people make decisions. Healthy adults aged 18 to 55 will experience different emotional triggers—such as heat, cold, or math problems—and then perform computer tasks while their brain activity is measured. The goal is to understand the link between emotions, thinking, and behavior, which may help improve diagnosis and treatment for mental disorders.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could help scientists better understand how emotions affect choices, potentially guiding future treatments for mental health disorders.
What could go wrong
This is an observational study with no treatment being tested. Results may not directly apply to people with mental health conditions, and the findings are exploratory.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.