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Pee test could replace pap smear for some women

NCT ID NCT03598946

First seen Jun 08, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study tested whether offering a home urine test for human papillomavirus (HPV) could encourage more women to get screened for cervical cancer. The trial targeted women aged 30–65 in Brittany, France, who had not responded to an initial invitation for a Pap smear. Participants received a kit to collect a urine sample at home and mail it to a lab. If the test was positive for high-risk HPV, they were urged to follow up with a doctor for a Pap smear. The study aimed to see if this at-home option would boost screening participation, especially among women from lower socioeconomic backgrounds. However, the trial was terminated early, so the full results are not available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Christopher PAYAN

    Brest, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

urinary test (home HPV urine test)

What this could lead to

If successful, this approach could offer a convenient, at-home screening option to reach women who avoid traditional Pap smears, potentially catching more cervical cancers early.

What could go wrong

The study was terminated early, so results are limited. Home urine tests may be less accurate than a clinic-based Pap smear, and the approach may not work equally well across all socioeconomic groups.

Conditions

The condition(s) this trial relates to.

cervical carcinoma Ovarian Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.