Pee test could replace pap smear for some women
NCT ID NCT03598946
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether offering a home urine test for human papillomavirus (HPV) could encourage more women to get screened for cervical cancer. The trial targeted women aged 30–65 in Brittany, France, who had not responded to an initial invitation for a Pap smear. Participants received a kit to collect a urine sample at home and mail it to a lab. If the test was positive for high-risk HPV, they were urged to follow up with a doctor for a Pap smear. The study aimed to see if this at-home option would boost screening participation, especially among women from lower socioeconomic backgrounds. However, the trial was terminated early, so the full results are not available.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- urinary test (home HPV urine test)
- What this could lead to
- If successful, this approach could offer a convenient, at-home screening option to reach women who avoid traditional Pap smears, potentially catching more cervical cancers early.
- What could go wrong
- The study was terminated early, so results are limited. Home urine tests may be less accurate than a clinic-based Pap smear, and the approach may not work equally well across all socioeconomic groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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1,809 people
The number who actually took part.
- Started
-
Apr 2021
- Finished
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Nov 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 65 years
- Sex
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Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women from 30 to 65 years old who did not do uterine cervix smear and who live in Brittany Exclusion Criteria: * Women under 30 years or over 65 years * Women of 30-65 years who have responded to the uterine cervix smear invitation * Women who have had an uterine cervix smear raise * Women who have already had an uterine cervix smear within 3 years * Women who had a total hysterectomy
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Christopher PAYAN
Brest, France
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