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Home workouts could protect kidney transplant Patients' hearts

NCT ID NCT04123951

Disease control Sponsor: University of Leicester Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 12-week home-based exercise program can improve heart health in kidney transplant recipients. Half of the 50 participants will follow the exercise plan, while the other half continues usual care. Researchers will use detailed MRI scans to measure changes in heart structure and function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
home-based exercise program
What this could lead to
If it works, this could point toward a simple, low-cost way to reduce heart disease risk in kidney transplant recipients.
What could go wrong
This is a small pilot study with only 50 participants, so results may not apply to everyone. The exercise program is short (12 weeks) and may not produce lasting heart benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2020

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age great than 18 years old * Prevalent RTR longer than 1year * Able and willing to give informed consent * Increased cardiometabolic risk, with at least one of: Diabetes mellitus Dyslipidaemia Hypertension History of ischaemic heart disease or cerebrovascular disease Obesity (BMI above 30) Exclusion Criteria: * Unable to undertake exercise due to physical or psychological barriers * Unable to undergo CMR scanning (incompatible implants, claustrophobia, allergy to agents) * Contraindication to exercise training (American College of Sports Medicine guidelines) * Female participants who are pregnant, lactating, or planning pregnancy during the course of the study. * Scheduled elective surgery or other procedures requiring general anaesthesia during the study. * Any other significant disease or disorder (i.e. significant co-morbidity including unstable hypertension, potentially lethal arrhythmia, myocardial infarction within 6 months, unstable angina, active liver disease, uncontrolled diabetes mellitus (HbA1c greater than or equal to 9%), advanced cerebral or peripheral vascular disease) which, in the opinion of the patient's own clinician the Principle Investigator may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study. * Inability to give informed consent or comply with testing and training protocol for any reason.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney transplant; complications

Contacts and locations

Locations

  • University Hospital Leicester NHS Trust

    Leicester, Leicestershire, LE5 4PW, United Kingdom

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Other studies related to the condition(s) this trial covers.