University Of Leicester

This large international trial aims to find the best treatment strategy for people with severe narrowing of the aortic heart valve who don't yet have symptoms. It will compare two approaches: performing valve replacement surgery early versus the current standard of careful monito…

This study is testing whether a 12-week low-calorie diet can improve symptoms, heart function, and exercise ability in adults with a common type of heart failure linked to obesity and type 2 diabetes. Sixty-three participants will be randomly assigned to either start the diet imm…

This study is testing whether a new wearable device and computer software can safely and effectively monitor brain blood flow in people at home. It will involve 140 people, including healthy older adults and those who have had a stroke, dementia, depression, or delirium. The main…