Home BP checks may prevent dangerous drops during dialysis
NCT ID NCT05159999
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study tests whether measuring blood pressure at home, rather than only at the dialysis center, helps prevent dangerous blood pressure drops during dialysis. 200 adults with end-stage kidney disease on dialysis will be assigned to either home or clinic blood pressure targets. The goal is to improve safety and reduce symptoms like fatigue and cramping.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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200 people
The number who actually took part.
- Started
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Feb 2022
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or older * Undergoing in-center, thrice weekly hemodialysis for treatment of end stage renal disease (ESRD) * Greater than 3 months since initiation of dialysis * No anticipated change to peritoneal dialysis or kidney transplant within 10 months * Life expectancy greater than 10 months * Hypertension (defined as mean pre-dialysis SBP \> 140 mmHg over prior 2 weeks or taking BP medications) * Able to obtain/measure a brachial blood pressure at dialysis and at home (e.g., no left ventricular assist device, blood pressure not been taken routinely in lower extremity at dialysis unit) * No condition that the primary nephrologist or PIs feel precludes participation Exclusion Criteria: * Incarcerated or institutionalized (prohibits home blood pressure measurement) * Participating in another intervention study that may affect blood pressure * Pregnant or anticipated pregnancy or breastfeeding (as this will require increase to more than three times a week dialysis and/or preclude use of some classes of blood pressure medications)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of California San Francisco
San Francisco, California, 94143, United States
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University of Washington
Seattle, Washington, 98104, United States
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