Blood sugar sensitivity may determine heart procedure success
NCT ID NCT07551947
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks if insulin resistance (when your body doesn't use insulin well) can predict whether a heart procedure called pulsed field ablation will work for people with atrial fibrillation (an irregular heartbeat). About 120 non-diabetic patients having their first ablation will give a blood sample before the procedure. Researchers will measure insulin resistance and follow up 4-5 months later to see who needs a repeat procedure. The goal is to find out if treating insulin resistance could improve ablation success.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Apr 2026
- Expected to finish
-
Dec 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Non-diabetic adults with atrial fibrillation (paroxysmal or persistent) indicated for first catheter ablation using pulsed field ablation at a single tertiary cardiology center (Cardiocentrum, AGEL Hospital Trinec-Podlesi, Czech Republic).
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>= 18 years * Undergoing first catheter ablation for atrial fibrillation using pulsed field ablation (PFA) * No known diagnosis of diabetes mellitus * Signed written informed consent Exclusion Criteria: * Known diabetes mellitus or active antidiabetic treatment * Previous atrial fibrillation ablation by any method * Pregnancy * Severe renal insufficiency (eGFR \< 30 mL/min) * Other severe comorbidities limiting follow-up * Inability to provide informed consent
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Artificial intelligence are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Kardiocentrum, Nemocnice AGEL Trinec-Podlesi a.s.
Třinec, 73961, Czechia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next
- Two ways to quiet a racing heart: trial pits hybrid ablation against standard catheter treatment
- Stroke's hidden heart rhythm clue under investigation
- Suture device may get heart patients walking sooner after leg vein procedures
- Two ways to catch a hidden heart rhythm after stroke
- Can a guided AI chatbot help women make better screening decisions?