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Massive HIV study aims to improve care for thousands in south africa

NCT ID NCT05886530

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study is tracking over 15,500 people with HIV at 24 healthcare facilities in South Africa. Researchers are comparing different ways of delivering HIV treatment and care to see which models work best for patients and healthcare providers. The study looks at viral suppression, patient satisfaction, costs, and how clinics use their resources.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help policymakers improve HIV treatment programs, making them more efficient and patient-friendly.
What could go wrong
This is an observational study, not a treatment trial. It collects data but does not test a new drug or intervention, so it won't directly change patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 15,520 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2021

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Clients using the South African public health system and providers employed by that system.

Ages

15 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Inclusion criteria for the time and motion study are: * Patient-facing or patient-supporting service provider at the study site (patient-supporting providers include data clerks, pharmacists, etc.) * Directly or indirectly involved in the site's implementation of ART and DSD models * Employed in current role at the study site for at least six months * Provides written informed consent to participate Inclusion criteria for provider interviews are: * Direct or indirect service provider at the study site (indirect providers include supervisors, technical advisors, etc.) * Directly or indirectly involved in the site's implementation of ART and DSD models * Employed in current role at the study site for at least six months * Provides written informed consent to participate. Inclusion criteria for the patient survey are: * Living with HIV and on ART for at least six months at the study site * ≥ 18 years old (18 and older considered adult for research purposes in South Africa) * Enrolled in a specified model of care (including conventional care) up to the target number of participants for that model and have received at least one medication refill under this model * Provide written informed consent to participate. Inclusion criteria for the testing survey are: * Undergoing HIV testing at the study site or other testing site within the catchment area * ≥ 18 years old (18 and older considered adult for research purposes in South Africa) * Provide written informed consent to participate. Exclusion Criteria: Exclusion criteria for the time and motion study are: ● None. Exclusion criteria for provider interviews are: ● None. Exclusion criteria for the patient survey are: * Unable to communicate in any of the languages into which the questionnaire has been translated or that is known to the research assistant * Not physically, mentally, or emotionally able to participate in the study, in the opinion of the investigators or study staff. * Unwilling to take the time required to complete the questionnaire on the day of consent. Exclusion criteria for the testing survey are: * Unable to communicate in any of the languages into which the questionnaire has been translated or that is known to the research assistant * Not physically, mentally, or emotionally able to participate in the study, in the opinion of the investigators or study staff. * Unwilling to take the time required to complete the questionnaire on the day of consent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Health economics and Epidemiology Research Office

    Johannesburg, South Africa

More trials for these conditions

Other studies related to the condition(s) this trial covers.