Double-Dose HIV drug may work with TB therapy in small study
NCT ID NCT05630872
First seen Dec 08, 2025 · Last updated May 24, 2026 · Updated 31 times
Summary
This study tested whether taking a double dose of the HIV drug dolutegravir (50 mg twice daily) along with the tuberculosis drug rifapentine is safe and maintains HIV viral suppression. Thirty adults with both HIV and tuberculosis participated. The goal was to see if the higher dose compensates for drug interactions, helping control both diseases.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Durban International CRS (Site # 11201)
Westridge, Durban RSA, 4091, South Africa
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South African Tuberculosis Vaccine Initiative (SATVI) CRS (Site # 31793)
Worcester, Western Province, 6850, South Africa
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Thai Red Cross AIDS Research Centre (TRC-ARC) CRS (Site # 31802)
Bangkok, 6850, Thailand
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University of Cape Town Lung Institute (UCTLI) CRS (Site # 31792)
Mowbray, Cape Town, Western Cape, 7700, South Africa
Conditions
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