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HIV patients may ditch one drug without losing viral control

NCT ID NCT02302547

First seen Jan 04, 2026 · Last updated Jun 17, 2026 · Updated 25 times

Summary

This study tested whether people with HIV who have a low viral reservoir can safely switch from a three-drug regimen to a two-drug regimen (Truvada alone) while keeping the virus under control. The goal is to reduce long-term side effects and treatment costs. The trial involved 224 participants with well-controlled HIV and looked at viral load after 48 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de NANCY

    Nancy, 54035, France

  • Centre de diagnostic et thérapeutique, Hopital Hotel Dieu

    Paris, 94010, France

  • Consultation Maladies Infectieuses, Chu de Poitiers, Cedex

    Poitiers, 86021, France

  • Hospital Tenon

    Paris, 75970, France

  • Maladies Infectieuses, CHU de ROUEN

    Rouen, 76031, France

  • Médecine Interne, Hôpital FOCH

    Suresnes, 92151, France

  • Service Universitaire des Maladies Infectieuses et du Voyageur, CH DRON

    Tourcoing, 59200, France

  • Service d'Immunologie Clinique centre de Vaccination anti- VIH ANRS Hopital Henri- Mondor

    Créteil, 94010, France

  • Service de Medecine Interne et Maladies Infectieuses, CHRU BRETONNEAU, TOURS CEDEX9

    Tours, 37044, France

  • Service de Médecine Interne et Maladies Infectieuses, Groupe Hospitalier La Rochelle, Cedex 01

    La Rochelle, 17019, France

  • Service de Médecine Interne, CH de SAINTONGE- BP 326

    Saintes, 17108, France

  • Service de Pneumologie, centre Hospitalier Fontenoy, CH de CHARTRES

    Le Coudray, 28630, France

  • Service des Maladies Infectieuses et tropicales, APHP SAINT LOUIS

    Paris, 75475, France

  • Service des Maladies Infectieuses, CHR Orléans La Source, ORLEANS CEDEX 2

    CHR d'ORLEANS, 45067, France

  • Service des maladies Infectieuses et tropicales, CH GEORGES RENON

    Niort, 79021, France

  • Unité des Maladies Infectieuses, CHU de CAEN

    Caen, 14033, France

Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.