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Can texting and cash help young people with HIV stay healthy?

NCT ID NCT04432571

Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study in Kenya tests different behavioral strategies to help 880 adolescents and young adults (ages 14-24) with HIV stay engaged in care. Participants first get either standard care or electronic navigation. If they miss appointments or have unsuppressed virus, they are re-randomized to more support, including peer navigation or cash transfers. The goal is to find the most effective and affordable way to improve viral suppression and retention in care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
behavioral interventions (electronic navigation, peer navigation, conditional cash transfers)
What this could lead to
If successful, this could identify cost-effective ways to help young people with HIV stay in care and keep the virus under control.
What could go wrong
This is a behavioral study, not a drug trial, so results may not apply to other settings. Success depends on participants' willingness to engage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

880 people

The number who actually took part.

Started

Apr 2021

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 to 24 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * HIV-infection, on or initiating ART, * 14-24 years of age, * Living \> 6 months in Kisumu County, Kenya in previous year, * Capable of informed consent (\> 18 years) or with a legal caregiver available for consent (14-\<18 years), * Access to a cell phone, * Ability to read or be read short message service (SMS) messages, * Willingness to be contacted by clinic upon missed appointment, * For AYA who report phone sharing must have disclosed to the person sharing the phone. * Additionally, we will include AYA who are aware of their HIV status or whose caregivers agree to assisted disclosure. Exclusion Criteria: * AYA who participated in ADAPT-R, * Those planning to move out of Kisumu County, those acutely ill and requiring hospitalization, * Those who report sharing phones but have not disclosed to the person sharing the phone

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV/AIDS

Contacts and locations

Locations

  • Kenya Medical Research Institute

    Kisumu, Kenya

More trials for these conditions

Other studies related to the condition(s) this trial covers.