Could short bursts of intense exercise boost heart recovery better than steady workouts?
NCT ID NCT07619664
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two supervised treadmill exercise programs for people recovering from coronary artery disease or a heart procedure. One group does high-intensity interval training (HIIT) — short, hard efforts with rest periods — while the other does moderate-intensity continuous training (MICT) — steady, moderate exercise. Researchers will measure changes in heart function, walking ability, and cholesterol levels to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT)
- What this could lead to
- If HIIT proves superior, it could become a standard exercise option in cardiac rehab, potentially improving heart function and fitness more efficiently than traditional moderate exercise.
- What could go wrong
- This is a small, early-stage trial with 66 participants, so results may not apply to all heart patients. HIIT is intense and may not be suitable for everyone, even with medical clearance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-60 years. * Diagnosed with stable coronary artery disease confirmed by angiography, stress testing, or echocardiography. * Left ventricular ejection fraction ≥45%. * Functional NYHA Class I or II. * Medically cleared by a cardiologist to participate in exercise (including recent ECG or stress test if necessary). * Lightly active lifestyle prior to study (not involved in structured exercise programs). Exclusion Criteria: * Unstable angina or recent myocardial infarction (within the past 6 weeks). * Uncontrolled hypertension (systolic BP \>180 mmHg or diastolic BP \>110 mmHg). * Severe valvular heart disease, arrhythmias, or left ventricular dysfunction (EF \<35%). * Musculoskeletal disorders (e.g., severe osteoarthritis, recent fractures, or surgeries) preventing safe participation in exercise. * Neurological disorders affecting mobility or safe exercise (e.g., stroke, Parkinson's disease). * Uncontrolled diabetes mellitus (HbA1c \>9% or recent hypoglycemia). * Any other condition judged by the investigator to make participation unsafe.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ch Pervaiz Elahi institute of cardiology Multan.
Multan, Punjab Province, 60000, Pakistan
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