Heart rehab gets a HIIT: study tests best way to boost fitness
NCT ID NCT04555512
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two methods of prescribing high-intensity interval training (HIIT) for people in cardiac rehabilitation. Thirty adults with heart conditions will follow a 12-week exercise program to see which prescription approach improves fitness, heart function, and oxygen use better. The goal is to find the most effective way to help heart patients recover through exercise.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-intensity interval training (HIIT) exercise program
- What this could lead to
- If successful, this could help doctors prescribe better exercise routines for heart patients, leading to improved fitness and recovery.
- What could go wrong
- This is a small, early-stage study with only 30 participants, so results may not apply to all heart patients. The exercise program may be too intense for some.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult 18 years and older. * English speaking. * Able to provide consent. * Has a qualifying indication for center-based cardiac rehabilitation that is non-surgical (i.e., Acute coronary syndrome, myocardial infarction, percutaneous coronary intervention, and stable angina). Exclusion Criteria: * Participants referred to cardiac rehabilitation following coronary artery bypass surgery, heart valve repair/replacement, heart transplant, or those with ventricular assist devices. * Patients who are unable to engage in a regularly structured exercise training program as part of a clinically indicated center-based outpatient cardiac rehabilitation program are not eligible. * Patients unable/unwilling to provide informed consent will not be enrolled. * Patients identified as having a contraindication to high intensity exercise.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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