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Could 15-Minute workouts recharge aging muscle cells?

NCT ID NCT05934760

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This study looks at how aging affects the power plants (mitochondria) inside muscle cells, and whether a short home-based exercise program can improve their function. Healthy adults of different ages will be compared, and older participants will do either high-intensity interval training or resistance band exercises for four weeks. Researchers will measure mitochondrial activity before and after to see if exercise can reverse age-related declines.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-intensity interval training (HIIT) and resistance-based training
What this could lead to
If successful, this could point toward simple home-based exercise routines that help preserve muscle strength and energy in older age.
What could go wrong
This is a small early-stage study, and results may not apply to everyone. Exercise programs can be challenging, and adherence may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Dec 2019

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ● Healthy male or female aged over 18 years old able to give informed, written consent. Exclusion Criteria: * ● Current participation in a formal exercise regime * Inability to use a static exercise bike * A BMI \<18 or \>35 kg/m2 * Active cardiovascular disease: * Uncontrolled hypertension (BP \> 160/100) * Angina * Heart failure (class III/IV) * Significant arrhythmia * Right to left cardiac shunt * Recent cardiac event * Taking beta-adrenergic blocking agents * Cerebrovascular disease: * Previous stroke * Aneurysm (large vessel or intracranial) * Epilepsy * Respiratory disease including: * Pulmonary hypertension * Significant COPD * Uncontrolled asthma * Malignancy * Clotting dysfunction * Significant musculoskeletal or neurological disorders * Any suspected or confirmed diagnosis of Covid-19

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Conditions

The condition(s) this trial relates to.

Motor Activity Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Graduate Entry Medical School, University of Nottingham, Royal Derby Hospital

    Derby, Derbyshire, DE223NE, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.