Could 15-Minute workouts recharge aging muscle cells?
NCT ID NCT05934760
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This study looks at how aging affects the power plants (mitochondria) inside muscle cells, and whether a short home-based exercise program can improve their function. Healthy adults of different ages will be compared, and older participants will do either high-intensity interval training or resistance band exercises for four weeks. Researchers will measure mitochondrial activity before and after to see if exercise can reverse age-related declines.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High-intensity interval training (HIIT) and resistance-based training
- What this could lead to
- If successful, this could point toward simple home-based exercise routines that help preserve muscle strength and energy in older age.
- What could go wrong
- This is a small early-stage study, and results may not apply to everyone. Exercise programs can be challenging, and adherence may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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32 people
The number who actually took part.
- Started
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Dec 2019
- Finished
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Mar 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ● Healthy male or female aged over 18 years old able to give informed, written consent. Exclusion Criteria: * ● Current participation in a formal exercise regime * Inability to use a static exercise bike * A BMI \<18 or \>35 kg/m2 * Active cardiovascular disease: * Uncontrolled hypertension (BP \> 160/100) * Angina * Heart failure (class III/IV) * Significant arrhythmia * Right to left cardiac shunt * Recent cardiac event * Taking beta-adrenergic blocking agents * Cerebrovascular disease: * Previous stroke * Aneurysm (large vessel or intracranial) * Epilepsy * Respiratory disease including: * Pulmonary hypertension * Significant COPD * Uncontrolled asthma * Malignancy * Clotting dysfunction * Significant musculoskeletal or neurological disorders * Any suspected or confirmed diagnosis of Covid-19
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Graduate Entry Medical School, University of Nottingham, Royal Derby Hospital
Derby, Derbyshire, DE223NE, United Kingdom
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