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ER study tests higher buprenorphine dose to boost opioid treatment success

NCT ID NCT06494904

First seen Jun 02, 2026 · Last updated Jun 10, 2026 · Updated 1 time

Summary

This study tests whether a higher starting dose of buprenorphine in the emergency room helps more people with opioid use disorder engage in treatment within 10 days. It also looks at whether the higher dose reduces cravings, withdrawal symptoms, and use of illicit opioids. The trial enrolls 360 adults with moderate to severe opioid use disorder who are currently not in treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cooper University Hospital

    RECRUITING

    Camden, New Jersey, 08103, United States

    Contact

    Contact Email: •••••@•••••

  • Highland Hospital

    RECRUITING

    Oakland, California, 94602, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Maine Medical Center

    RECRUITING

    Portland, Maine, 04102, United States

    Contact

    Contact Email: •••••@•••••

  • San Leandro Hospital

    RECRUITING

    San Leandro, California, 94578, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah Hospital

    RECRUITING

    Salt Lake City, Utah, 84132, United States

    Contact Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.