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New nasal therapy could bring relief to patients struggling to breathe

NCT ID NCT07552935

Symptom relief Sponsor: Tampere University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study looks at whether high-flow nasal therapy can help relieve severe breathlessness in people receiving palliative care. About 40 patients will try both the nasal therapy and a fan blowing air on their face for 30 minutes each. Researchers will ask how their breathing feels after each treatment to see which works better. The goal is to find a simple, low-risk way to improve comfort for those with incurable illness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The patient is in palliative care (ICD-10 diagnostic code Z51.5 palliative care) * Age ≥ 18 years * Ability to understand the study and provide informed consent to participate * Significant breathlessness (NRS = Numeric Rating Scale ≥ 4). * The treating physician has assessed that the patient would not benefit from treatment in intensive care unit or monitor unit. * The treating physician has assessed that the patient would not benefit from invasive mechanical ventilation (intubation) or cardiopulmonary resuscitation. Exclusion Criteria: * Decreased level of consciousness, delirium, or other lack of cooperation that prevents participation. * Respiratory support other than HFNT is required. * The patient has received HFNT during the same admission to palliative care ward or hospice. * The cause of dyspnea can be treated immediately. * Inability to provide informed consent to participate.

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Conditions

The condition(s) this trial relates to.

Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breathlessness Palliative care

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hatanpää hospital, Palliative Care Centre and Home Hospital Services, Wellbeing Services County of Pirkanmaa, Tampere University Hospital

    RECRUITING

    Tampere, 33900, Finland

  • Pirkanmaa Hospice

    RECRUITING

    Tampere, 33520, Finland

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