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Cure My Disease

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New short-course malaria cure could save thousands

NCT ID NCT05879224

Cure Sponsor: Menzies School of Health Research Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to cure vivax malaria, a type of malaria that can come back. Researchers gave a high daily dose of the drug primaquine for a short time, but only after a quick test to check for a genetic condition (G6PD deficiency) that could cause serious side effects. About 3000 people with vivax malaria in Indonesia took part. The goal was to see if this approach is safe and practical in real-world clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

2,999 people

The number who actually took part.

Started

Aug 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 months and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with vivax malaria Exclusion Criteria: * Patients who are pregnant * Patients who are breastfeeding * Patients with a Hb \<8g/dL * Patients with a previous adverse reaction to primaquine * Patient with severe malaria

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Conditions

The condition(s) this trial relates to.

G6PD deficiency Plasmodium vivax malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

G6PD deficiency Vivax malaria

Contacts and locations

Locations

  • Puskesmas Bhintuka

    Mimika, Special Region of Papua, Indonesia

  • Puskesmas Hanura

    Hanura, Lampung, Indonesia

  • Puskesmas Pasar Sentral

    Mimika, Special Region of Papua, Indonesia

  • Puskesmas Tanjung Leidong

    Labuhanbatu, North Sumatra, Indonesia

  • Puskesmas Timika

    Mimika, Special Region of Papua, Indonesia

  • Puskesmas Wania

    Mimika, Special Region of Papua, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.