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High-Dose antifungal shows promise against deadly fungus

NCT ID NCT00467883

First seen Mar 07, 2026 · Last updated Apr 29, 2026 · Updated 9 times

Summary

This study tested a high dose (10 mg/kg/day) of the antifungal drug Ambisome in 40 people with zygomycosis, a rare but serious fungal infection. The goal was to see if the treatment could control the infection, measured by complete or partial response after 4 weeks. Researchers also tracked side effects and survival at 15 days.

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Contacts and locations

Locations

  • Hôpital Necker - Service des Maladies Infectieuses et Tropicales

    Paris, 75015, France

  • Necker Hospital

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.