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Can a nasal tube boost exercise in heart failure? new trial investigates

NCT ID NCT07613762

Symptom relief Sponsor: Universidad de Santiago de Chile Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a high-flow nasal cannula (a device that delivers warm, moist air through the nose) can help people with heart failure exercise longer during cardiac rehab. Twenty-eight adults will do two treadmill tests—one with the device and one without—to compare endurance and perceived effort. The goal is to see if this simple tool can make exercise easier and more effective for heart failure patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-flow nasal cannula (HFNC) device
What this could lead to
If it works, this could show that using a simple breathing device during exercise helps heart failure patients tolerate activity better, potentially improving rehab outcomes.
What could go wrong
This is a small, early-stage trial with only 28 participants. The device is used only during the test, so any benefit may be temporary and not translate to daily life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Medical diagnosis of heart failure (documented in clinical record or referral) * Electrocardiogram performed within the last 6 months * Functional capacity class II or III according to the New York Heart Association (NYHA) classification * Stable pharmacological treatment * Stable and controlled comorbidities * Available to complete two evaluation sessions * Able and willing to provide written informed consent Exclusion Criteria: * Diagnosis of respiratory disease (chronic obstructive pulmonary disease, interstitial lung disease, or pulmonary hypertension) * Myocardial infarction within the past 3 months * Hospitalization due to heart failure within the past 4 weeks * Cognitive impairment or inability to follow the study protocol * Neuromuscular or osteoarticular conditions that limit treadmill test performance

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Conditions

The condition(s) this trial relates to.

Dyspnea heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac rehabilitation Exercise tolerance (measured in minutes) Heart failure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Complejo Hospitalario San José

    Santiago, Santiago Metropolitan, 8380418, Chile

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