AI could help predict sudden cardiac death in hereditary heart disease patients
NCT ID NCT07257289
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to improve how doctors predict the risk of sudden cardiac death or heart failure in people with inherited heart diseases. Researchers will use artificial intelligence to analyze data from 1,000 participants, including medical history, ECGs, imaging, genetic tests, and biomarkers. The goal is to better identify who truly needs a defibrillator and who can avoid unnecessary procedures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a more accurate way to predict who is at risk of sudden cardiac death or heart failure, helping doctors decide who needs a defibrillator.
- What could go wrong
- This is an observational study, not a treatment trial. The AI model may not prove accurate enough to change clinical practice, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Dec 2036
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All adult and minor patients with hereditary heart disease or cardiomyopathies and their relatives.
- Ages
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1 year to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria : I. hereditary heart disease II. All relatives of patients III. Patients referred to the reference centre for suspected hereditary rhythm disorders or cardiomyopathies IV. Written consent V. social security scheme Exclusion Criteria : I. Patients participating in a therapeutic trial that may interfere with the research results II. Patients under guardianship or curatorship.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
15 sites in 3 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU de Bordeaux
NOT_YET_RECRUITINGBordeaux, France
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CHU de Brest
NOT_YET_RECRUITINGBrest, France
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CHU de Clermont-Ferrand
NOT_YET_RECRUITINGClermont-Ferrand, France
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CHU de Dijon
NOT_YET_RECRUITINGDijon, France
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CHU de La Rochelle
NOT_YET_RECRUITINGLa Rochelle, France
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CHU de Limoges
NOT_YET_RECRUITINGLimoges, France
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CHU de Montpellier
NOT_YET_RECRUITINGMontpellier, France
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CHU de Nantes
RECRUITINGNantes, 44093, France
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CHU de Poitiers
NOT_YET_RECRUITINGPoitiers, France
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CHU de Rennes
NOT_YET_RECRUITINGRennes, France
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CHU de Strasbourg
NOT_YET_RECRUITINGStrasbourg, France
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CHU de Toulouse
NOT_YET_RECRUITINGToulouse, France
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CHU de Tours
NOT_YET_RECRUITINGTours, France
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CHU de la Martinique
NOT_YET_RECRUITINGFort-de-France, Martinique
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CHU de la Réunion
NOT_YET_RECRUITINGSaint-Pierre, Reunion
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Other studies related to the condition(s) this trial covers.
- Do genes drive heart damage from irregular rhythms?
- Can heart surgery rehab move from hospital to home?
- Can a gene registry unlock the secrets of childhood heart failure?
- Can a heart pump spark its own recovery? a new study investigates
- Implanted sensors may foresee heart failure crises
- Can a Gene-Silencing drug tame a rare heart disease?