Pomegranate and neem mouthwashes take on chlorhexidine in schoolchildren oral health showdown
NCT ID NCT07309679
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two herbal mouthwashes (pomegranate peel extract and neem extract) against the standard chlorhexidine mouthwash in 156 school children aged 8-12. The goal was to see if the natural options could reduce plaque, gum inflammation, and harmful bacteria just as well, but with fewer side effects like tooth staining. Results will show whether herbal rinses are a good alternative for daily oral care in kids.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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156 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Nov 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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8 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 8 to 12 years (common age group for gingivitis). * Both male and female participants. * Plaque Index ≥ 1 according to Silness and Löe index. * Regular brushing habit (once per day). * Parental consent obtained prior to participation. Exclusion Criteria: * Children with systemic diseases or conditions affecting salivary flow. * Children with a history of antibiotic use within the last month before the study. * Those with known allergy or intolerance to any mouthwash ingredients. * Children currently using any other mouthwash or oral antiseptic.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Dentistry,Mansoura university
Al Mansurah, Dakahlia Governorate, 35516, Egypt
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Other studies related to the condition(s) this trial covers.
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